Organic Chemistry Lab II

1 Credits | 200 Level | 20 Contact hours

REQUIRED TEXTBOOKS AND COURSE MATERIALS

The text for this course is considered optional, but is an invaluable resource for anyone who
wants to understand the organic laboratory techniques and underlying theories. Older editions, but editions earlier than the fifth edition are not recommended due to significant changes.

Students using the earlier editions must determine on their own how the assigned readings
correlate to their copy of the text.

If you choose not to use the Zubrick text, the online Organic Chemistry Lab Techniques, by Lisa
Nichols is an open-access alternative (https://bit.ly/2wfC69S).


REQUIRED MATERIALS

1. Textbook: The Organic Chem Lab Survival Manual: A Student's Guide to Techniques,
10th ed. by James Zubrick
2. Laboratory Notebook: either a bound notebook (like a composition notebook) or a
laboratory notebook (like those used in Chem 1411/1611)
3. Approved laboratory safety goggles
4. Laboratory coat

DESCRIPTION

This course, in conjunction with CHEM 2321, is designed to introduce students to the methods,
equipment, instrumentation, and techniques involved in chemical synthesis. The laboratories this semester will focus on introducing students to common techniques for the separation, purification, and analysis of specific chemical compounds in reaction solutions and complex mixtures.

The ability to isolate pure compounds is vital to the synthesis of all varieties of chemicals for both
manufacturing and research purposes. The techniques introduced in this course are the same
techniques used for purifying and analyzing chemicals in research programs like those found in
Department of Chemistry here at the University of Virginia as well as in pharmaceutical and fine chemical labaratories throughout the worlds

STUDENT LEARNING/COURSE OUTCOMES

1 Course Introduction. Meet in laboratory at the following times:
2 Synthesis: Paracetamol (acetaminophen)
3 Purification: Recrystallization and Melting Point
4 Analysis: Thin-Layer and Gas Chromatography
5 Separation: Acid/Base Extraction
6 Characterization: IR Spectroscopy

ASSESSMENT/GRADES

Pre-Lab Preparation 10%
In-Lab Participation 10%
Post-Lab Assignment 60%
Final Exam 20%

*Course content subject to change